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Horizon Biotechnology Fund

A fund investing in innovative companies addressing high unmet medical needs or improving the standard of care in the fast-growing biotechnology sector.

Overview

Quarterly Update

Watch the investment team recap this quarter.

(Note: Filmed in October 2024).

INVESTMENT OBJECTIVE

The Biotechnology Fund aims to provide capital growth.

The Fund invests at least 80% of its net assets in equities and equity-related instruments of biotechnology and biotechnology-related companies worldwide. “Biotechnology and biotechnology-related companies” is defined as:

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• companies that are included in the NASDAQ Biotechnology Index;
• companies that develop small molecule or biologic drugs subject to the approval of global regulatory agencies;
• companies that market products or services to aid in the research and development of small molecule or biologic drugs; or
• companies that are considered such by the Investment Manager.

In choosing investments, the Investment Manager aims to select biotechnology companies that he or she believes to be undervalued, with greater potential for clinical and/or commercial success than is currently reflected in market prices.

The Fund may invest in companies of any size, including smaller capitalisation companies.

Equity-related instruments may include depository receipts and derivative instruments (such as futures, forwards, equity swaps (also known as contract-for-differences), swaps and options and warrants).

The Fund may use derivative instruments for investment purposes (up to 10% of its net assets) and hedging purposes. The underlyings consist of a range of securities or indices that the Fund may invest in according to the Fund’s investment objective and policy,

The Investment Manager may from time to time consider hedging currency and interest rates exposure, but will not generally enter into contracts involving a speculative position in any currency or interest rate.

On an ancillary basis and for defensive purposes, the Fund may invest in:
• convertible bonds and associated derivative instruments;
• cash, money market instruments or derivative instruments that are used to provide downside market protection or dampen market volatility.

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ABOUT THIS FUND

Experienced and Specialised Investment Team: Dedicated biotechnology specialists with deep scientific backgrounds and a distinguished record of investing in biotechnology stocks. This highly specialised team is supported by the larger Janus Henderson health care team with over a century of combined health care investing experience.

Differentiated Fundamental Research: Seek to understand the science and the business to identify opportunities and mitigate the clinical and commercial risks inherent in the sector.

Disciplined Investment Process: Balanced across development stage, early commercial and profitable biotechnology companies and augmented by a differentiated Value at Risk Framework designed to mitigate the volatility associated with drug development.

RATINGS AND AWARDS

RFL Awards Winner - Austria

RATINGS AND AWARDS

RFL Awards Winner - Europe

RATINGS AND AWARDS

RFL Awards Winner - France
RFL Awards Winner - Europe

RATINGS AND AWARDS

RFL Awards Winner - Germany

RATINGS AND AWARDS

RATINGS AND AWARDS

RATINGS AND AWARDS

RATINGS AND AWARDS

RATINGS AND AWARDS

TOP HOLDINGS

Top holdings can be found in the factsheet of the fund.

Portfolio Management

Andy Acker, CFA

Portfolio Manager

Industry since 1996. Joined Firm in 1999.

Daniel Lyons, Ph.D., CFA

Portfolio Manager | Research Analyst

Industry since 2000. Joined Firm in 2000.

Agustin Mohedas, Ph.D.

Portfolio Manager | Research Analyst

Industry since 2014.

Performance

Documents