Please ensure Javascript is enabled for purposes of website accessibility Global Life Sciences Fund - Janus Henderson Investors - US Institutional
For Institutional Investors in the US

Global Life Sciences Fund Holdings

Full Portfolio Holdings

(As of February 28, 2025)

% OF INVESTMENTS
Eli Lilly & Co 10.09
UnitedHealth Group Inc 5.97
AstraZeneca PLC 3.98
Novo Nordisk A/S 3.40
Johnson & Johnson 3.30
Abbott Laboratories 3.17
Boston Scientific Corp 3.08
Sanofi SA 2.88
Amgen Inc 2.77
AbbVie Inc 2.74
Vertex Pharmaceuticals Inc 2.68
Thermo Fisher Scientific Inc 2.36
Novartis AG (ADR) 2.26
Argenx SE (ADR) 2.15
Intuitive Surgical Inc 2.08
Stryker Corp 1.77
Merck & Co Inc 1.74
Danaher Corp 1.69
Akero Therapeutics Inc 1.55
Ascendis Pharma A/S (ADR) 1.43
Roche Holding AG 1.41
Madrigal Pharmaceuticals Inc 1.29
McKesson Corp 1.22
Sarepta Therapeutics Inc 1.20
Vaxcyte Inc 1.15
HCA Healthcare Inc 1.13
Medtronic PLC 1.13
Globus Medical Inc 1.11
REVOLUTION Medicines Inc 1.07
Avidity Biosciences Inc 1.02
Cencora Inc 1.01
Lantheus Holdings Inc 0.97
Soleno Therapeutics Inc 0.92
DexCom Inc 0.88
Elevance Health Inc 0.86
Penumbra Inc 0.81
Zoetis Inc 0.81
Teva Pharmaceutical Industries Ltd (ADR) 0.78
CVS Health Corp 0.76
Verona Pharma PLC (ADR) 0.75
Humana Inc 0.73
Biohaven Ltd 0.72
Mirum Pharmaceuticals Inc 0.69
Inspire Medical Systems Inc 0.61
Edwards Lifesciences Corp 0.60
Bridgebio Pharma Inc 0.60
Zai Lab Ltd (ADR) 0.58
Gilead Sciences Inc 0.57
Cooper Cos Inc 0.57
89bio Inc 0.56
PTC Therapeutics Inc 0.55
Dyne Therapeutics Inc 0.49
Ardelyx Inc 0.45
Centene Corp 0.45
Align Technology Inc 0.44
Teleflex Inc 0.42
Avadel Pharmaceuticals PLC 0.40
Travere Therapeutics Inc 0.40
STERIS PLC 0.39
United Therapeutics Corp 0.38
Edgewise Therapeutics Inc 0.36
Arcellx Inc 0.36
Janux Therapeutics Inc 0.36
Ideaya Biosciences Inc 0.34
Illumina Inc 0.34
Legend Biotech Corp (ADR) 0.33
Alnylam Pharmaceuticals Inc 0.32
Insmed Inc 0.30
Neurocrine Biosciences Inc 0.30
Sotera Health Co 0.30
Structure Therapeutics Inc (ADR) 0.28
Rhythm Pharmaceuticals Inc 0.28
ICON PLC 0.27
Hoya Corp 0.26
Xenon Pharmaceuticals Inc 0.26
Amicus Therapeutics Inc 0.26
Crinetics Pharmaceuticals Inc 0.24
Cytokinetics Inc 0.23
IQVIA Holdings Inc 0.18
CG oncology Inc 0.16
NeoGenomics Inc 0.16
Apogee Therapeutics Inc 0.16
Immunome Inc 0.16
Metsera Inc 0.15
Praxis Precision Medicines Inc 0.14
Rocket Pharmaceuticals Inc 0.13
Heartflow Inc 0.12
Bicara Therapeutics Inc 0.12
Curevo Inc 0.11
Geron Corp 0.10
4D Molecular Therapeutics Inc 0.08
Attralus Inc 0.08
Element Biosciences Inc 0.07
Magnolia Medical Technologies Inc 0.06
Asher Biotherapeutics Inc 0.06
Shoreline Biosciences Inc 0.06
Green Cross Holdings Corp 0.05
HeartFlow Inc, 0.00%, 12/02/24 0.04
Sonoma Biotherapeutics Inc 0.04
Lexeo Therapeutics Inc 0.04
Freenome Holdings Inc 0.04
Freenome Holdings Inc 0.04
Asher Biotherapeutics Inc 0.03
Twinstrand Biosciences Inc 0.03
Sonoma Biotherapeutics Inc 0.02
Cargo Therapeutics Inc 0.02
Bicara Therapeutics Inc 0.01
Hemoshear Therapeutics LLC 0.01
Magnolia Medical Technologies 0.00
Clementia Pharmaceuticals Inc 0.00
Cash & Equivalents 0.17
Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio. Securities are reported at market value.
The portfolio data and its presentation here is based on the investment book of record and may differ from the accounting book of record and complete schedules of investments in regulatory filings due to differing accounting and reporting standards.