Please ensure Javascript is enabled for purposes of website accessibility Global Life Sciences Diversified ADR Managed Account - Janus Henderson Investors - US Advisor
For Financial Professionals in the US

Global Life Sciences Diversified ADR Managed Account Holdings

Full Portfolio Holdings

(As of 12/31/2025)

% OF INVESTMENTS
Eli Lilly & Co 9.56
Johnson & Johnson 5.57
AstraZeneca PLC (ADR) 4.32
UnitedHealth Group Inc 3.47
AbbVie Inc 3.47
Argenx SE (ADR) 2.75
Abbott Laboratories 2.64
Novartis AG (ADR) 2.52
Praxis Precision Medicines Inc 2.42
Boston Scientific Corp 2.37
Sanofi SA (ADR) 2.33
Thermo Fisher Scientific Inc 2.31
Intuitive Surgical Inc 2.26
Amgen Inc 2.15
Vertex Pharmaceuticals Inc 2.12
Roche Holding AG (ADR) 2.10
Bridgebio Pharma Inc 2.10
HCA Healthcare Inc 1.97
REVOLUTION Medicines Inc 1.94
Danaher Corp 1.82
Stryker Corp 1.65
CVS Health Corp 1.54
Madrigal Pharmaceuticals Inc 1.50
Ascendis Pharma A/S (ADR) 1.50
McKesson Corp 1.35
Globus Medical Inc 1.25
Teva Pharmaceutical Industries Ltd (ADR) 1.20
Gilead Sciences Inc 1.15
Medtronic PLC 1.15
Mirum Pharmaceuticals Inc 1.15
PTC Therapeutics Inc 1.14
Elevance Health Inc 1.07
Travere Therapeutics Inc 1.03
Cencora Inc 1.03
United Therapeutics Corp 1.03
Avidity Biosciences Inc 1.00
Dyne Therapeutics Inc 0.93
Soleno Therapeutics Inc 0.91
Vaxcyte Inc 0.86
Structure Therapeutics Inc (ADR) 0.75
Edwards Lifesciences Corp 0.74
Medline Inc 0.69
Lantheus Holdings Inc 0.69
Daiichi Sankyo Co Ltd (ADR) 0.68
Becton Dickinson & Co 0.59
Penumbra Inc 0.58
Apogee Therapeutics Inc 0.55
Regeneron Pharmaceuticals Inc 0.54
Glaukos Corp 0.53
DexCom Inc 0.53
Cooper Cos Inc 0.52
Ideaya Biosciences Inc 0.51
Tarsus Pharmaceuticals Inc 0.42
STERIS PLC 0.42
Nuvalent Inc 0.38
Alnylam Pharmaceuticals Inc 0.37
Neurocrine Biosciences Inc 0.37
Sotera Health Co 0.36
Zoetis Inc 0.35
Olema Pharmaceuticals Inc 0.33
Ardelyx Inc 0.33
Edgewise Therapeutics Inc 0.33
Crinetics Pharmaceuticals Inc 0.31
Centene Corp 0.28
Arcellx Inc 0.28
Scholar Rock Holding Corp 0.27
Cogent Biosciences Inc 0.27
Protagonist Therapeutics Inc 0.27
Terns Pharmaceuticals Inc 0.27
Xenon Pharmaceuticals Inc 0.26
Inspire Medical Systems Inc 0.26
Teleflex Inc 0.26
Illumina Inc 0.25
Insmed Inc 0.24
Humana Inc 0.24
Insulet Corp 0.20
Avadel Pharmaceuticals PLC 0.20
Janux Therapeutics Inc 0.18
Biohaven Ltd 0.18
PFIZER INC 0.04
Novo Nordisk A/S 0.01
Cash & Equivalents 1.54
Janus Henderson publishes this listing of securities held as of the most recently available disclosure period, which varies depending on the portfolio. Any portion of holdings may be excluded from publication when deemed in the best interest of the portfolio. Securities are reported at market value.