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For financial professionals in Belgium

Global Life Sciences Fund

By understanding the science and business of health care, our experienced team invests in companies addressing unmet medical needs or those that seek to make the health care system more efficient.

ISIN
IE0009355771

NAV
USD 48.70
As of 17/04/2025

1-Day Change
USD 0.01 (0.02%)
 As of 17/04/2025

Morningstar Rating

As of 31/03/2025

Overview

INVESTMENT OBJECTIVE

Le Fonds vise à fournir une croissance du capital sur le long terme.
Objectif de performance: Surperformer par rapport à l'indice MSCI World Health Care Index d'au moins 2% par an, avant déduction des charges, sur une période quelconque de cinq ans.

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Le fonds investit au minimum 80 % de son actif dans des titres de capital (actions) émis par des entreprises de toutes tailles, notamment des petites capitalisations, présentes dans n’importe quel pays et actives dans le secteur des sciences de la vie. Jusqu’à 20 % du portefeuille peut être investi dans les marchés en développement.
Le fonds peut aussi investir dans d’autres actifs, notamment des liquidités et des instruments du marché monétaire.
Le gestionnaire par délégation peut également utiliser des produits dérivés (instruments financiers complexes) pour réduire les risques, gérer le fonds plus efficacement ou pour générer une croissance ou des revenus supplémentaires.
Le fonds est géré de manière active par rapport à l’indice MSCI World Health Care, qui est largement représentatif des entreprises dans lesquelles il peut investir, qui sont à la base de l’objectif de performance du fonds. Le gestionnaire par délégation peut, à sa discrétion, sélectionner des investissements à intégrer dans le fonds en appliquant des pondérations différentes de celles de l’indice, voire des titres absents des indices, mais, parfois, le fonds peut détenir des investissements dans les mêmes proportions que l’indice.

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The value of an investment and the income from it can fall as well as rise as a result of market and currency fluctuations and you may not get back the amount originally invested.
Potential investors must read the prospectus, and where relevant, the key investor information document before investing.
This website is a Marketing Communication and does not qualify as an investment recommendation.

ABOUT THIS FUND

  • Looks to invest in companies addressing unmet medical needs or those that seek to make the health care system more efficient
  • Aims to maintain a balanced portfolio across subsectors (biotechnology, health care services, medical devices and pharmaceuticals)
  • An experienced team of specialists that seeks to understand the science and the business of health care
Past performance does not predict future returns. 
 

Portfolio Management

Andy Acker, CFA: Portfolio Manager
Andy Acker, CFA

Portfolio Manager

Industry since 1996. Joined Firm in 1999.

Daniel Lyons, Ph.D., CFA: Portfolio Manager | Research Analyst
Daniel Lyons, Ph.D., CFA

Portfolio Manager | Research Analyst

Industry since 2000. Joined Firm in 2000.

Performance

Past performance does not predict future returns. All performance data includes both income and capital gains or losses and reflects the deduction of any ongoing charges or other fund expenses.
Cumulative & Annualised Performance (%)
As of 31/03/2025
A2 USD (Net) MSCI World Health Care NR Sector Equity Healthcare - OE
  
  Cumulative Annualised
  1MO YTD 1YR 3YR 5YR 10YR Since Inception
31/03/2000
A2 USD (Net) -4.63 0.51 -5.40 2.93 9.22 5.36 6.79
MSCI World Health Care NR -2.32 5.10 -1.10 2.58 9.89 7.01 7.42
Sector Equity Healthcare - OE -3.57 1.43 -3.67 -1.16 5.41 3.84 5.80
 
  Annualised
3YR 5YR 10YR Since Inception
31/03/2000
A2 USD (Gross) - 11.81 7.89 9.53
MSCI World Health Care NR + 2.00% - 12.09 9.15 9.57
Note that any differences among portfolio securities currencies, share class currencies and costs to be paid or represented in currencies other than your home currency will expose you to currency risk.  Costs and returns may increase or decrease as a result of currency and exchange rate fluctuations.
Performance/performance target related data will display only when relevant to the fund/share class inception date and the annualised target time period.
© Morningstar 2025. All rights reserved. NAV-NAV, gross income reinvested where applicable.
Fund charges will impact the value of your investment. In particular, the ongoing charges applicable to each fund will dilute investment performance, particularly over time.
The ongoing charges includes fees payable to Distributors. Where the ongoing charges exceed the target outperformance relative to the benchmark the return is likely to be below the benchmark return, even when the Fund’s outperformance target (before the deduction of charges) has been achieved.
Calendar Year Returns (%)
As of 31/03/2025
A2 USD (Net) MSCI World Health Care NR Sector Equity Healthcare - OE
YTD 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015
A2 USD (Net) 0.51 1.72 5.44 -4.35 4.72 23.41 27.06 2.01 20.55 -13.79 5.69
MSCI World Health Care NR 5.10 1.13 3.76 -5.41 19.80 13.52 23.24 2.51 19.80 -6.81 6.60
Sector Equity Healthcare - OE 1.43 -0.97 2.67 -13.91 7.12 20.53 21.80 -3.40 21.68 -9.37 5.90
Calendar Year Returns (%)
Year A2 USD (Net) Index
2024 1.72 1.13
2023 5.44 3.76
2022 -4.35 -5.41
2021 4.72 19.80
2020 23.41 13.52
2019 27.06 23.24
2018 2.01 2.51
2017 20.55 19.80
2016 -13.79 -6.81
2015 5.69 6.60
2014 32.75 18.10
2013 52.45 36.27
2012 22.47 17.54
2011 6.08 9.46
2010 6.04 2.41
2009 24.46 18.89
2008 -31.08 -21.50
2007 19.64 3.94
2006 -3.74 10.47
2005 9.89 9.00
2004 12.36 6.00
2003 25.55 19.50
2002 -31.32 -17.98
2001 -20.46 -13.24
2000 from 31/03/2000 16.80 25.65
Note that any differences among portfolio securities currencies, share class currencies and costs to be paid or represented in currencies other than your home currency will expose you to currency risk.  Costs and returns may increase or decrease as a result of currency and exchange rate fluctuations.
Performance/performance target related data will display only when relevant to the fund/share class inception date and the annualised target time period.
© Morningstar 2025. All rights reserved. NAV-NAV, gross income reinvested where applicable.
Fund charges will impact the value of your investment. In particular, the ongoing charges applicable to each fund will dilute investment performance, particularly over time.
The ongoing charges includes fees payable to Distributors. Where the ongoing charges exceed the target outperformance relative to the benchmark the return is likely to be below the benchmark return, even when the Fund’s outperformance target (before the deduction of charges) has been achieved.
Please note the performance target is to be achieved over a specific annualised time period. Refer to the performance target wording within the objective.

Recommended holding period 5 Years

Example Investment: USD 10,000

Scenarios If you exit after 1 year If you exit after 5 years
MinimumThere is no minimum guaranteed return. You could lose some or all of your investment
StressWhat you might get back after costs1,360 USD1,420 USD
Average return each year-86.43%-32.36%
UnfavourableWhat you might get back after costs7,630 USD10,310 USD
Average return each year-23.73%0.61%
ModerateWhat you might get back after costs10,490 USD14,840 USD
Average return each year4.93%8.21%
FavourableWhat you might get back after costs13,220 USD19,520 USD
Average return each year32.19%14.31%
This chart shows the fund’s performance as the percentage loss or gain per year over the last 10 years against its benchmark. It can help you to assess how the fund has been managed in the past and compare it to its benchmark.

As of 31/03/2025
A2 USD (Net) MSCI World Health Care NR Sector Equity Healthcare - OE
Note that any differences among portfolio securities currencies, share class currencies and costs to be paid or represented in currencies other than your home currency will expose you to currency risk.  Costs and returns may increase or decrease as a result of currency and exchange rate fluctuations.
Past performance does not predict future returns. The value of an investment may go down as well as up and you may lose the amount originally invested. Markets could develop very differently in the future. It can help you to assess how the fund has been managed in the past.
© Morningstar 2025. All rights reserved. NAV-NAV, gross income reinvested where applicable.
Fund charges will impact the value of your investment. In particular, the ongoing charges applicable to each fund will dilute investment performance, particularly over time.
Fee Information
Initial Charge 5.00%
Annual Charge 1.50%
Ongoing Charge
(As of 31/12/2023) 		2.38%
For more information about charges, please see our fund charges page or the “charges” section of the fund’s prospectus.

Portfolio

Top Holdings (As of 31/03/2025)
% of Fund
Eli Lilly & Co 9.41
UnitedHealth Group Inc 6.87
AstraZeneca PLC 4.00
Johnson & Johnson 3.59
Boston Scientific Corp 3.13
Abbott Laboratories 3.09
Sanofi SA 3.06
Amgen Inc 2.89
AbbVie Inc 2.83
Vertex Pharmaceuticals Inc 2.82
TOTAL 41.69
References made to individual securities do not constitute a recommendation to buy, sell or hold any security, investment strategy or market sector, and should not be assumed to be profitable. Janus Henderson Investors, its affiliated advisor, or its employees, may have a position in the securities mentioned.
Sector Allocation % of Fund % of Index % of Fund % of Index As of 31/03/2025
Regional Allocation % of Fund % of Index % of Fund % of Index As of 31/03/2025

Documents

Related Insights

Our intellectual capital is readily available and central to our Knowledge Shared approach"
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  • The value of the Funds and the income from them is not guaranteed and may fall as well as rise. You may get back less than you originally invested.
  • Past performance does not predict future returns.
  • Third party data is believed to be reliable, but its completeness and accuracy is not guaranteed.
  • Shares/Units can lose value rapidly, and typically involve higher risks than bonds or money market instruments. The value of your investment may fall as a result.
  • Shares of small and mid-size companies can be more volatile than shares of larger companies, and at times it may be difficult to value or to sell shares at desired times and prices, increasing the risk of losses.
  • If a Fund has a high exposure to a particular country or geographical region it carries a higher level of risk than a Fund which is more broadly diversified.
  • The Fund is focused towards particular industries or investment themes and may be heavily impacted by factors such as changes in government regulation, increased price competition, technological advancements and other adverse events.
  • The Fund may use derivatives to help achieve its investment objective. This can result in leverage (higher levels of debt), which can magnify an investment outcome. Gains or losses to the Fund may therefore be greater than the cost of the derivative. Derivatives also introduce other risks, in particular, that a derivative counterparty may not meet its contractual obligations.
  • If the Fund holds assets in currencies other than the base currency of the Fund, or you invest in a share/unit class of a different currency to the Fund (unless hedged, i.e. mitigated by taking an offsetting position in a related security), the value of your investment may be impacted by changes in exchange rates.
  • When the Fund, or a share/unit class, seeks to mitigate exchange rate movements of a currency relative to the base currency (hedge), the hedging strategy itself may positively or negatively impact the value of the Fund due to differences in short-term interest rates between the currencies.
  • Securities within the Fund could become hard to value or to sell at a desired time and price, especially in extreme market conditions when asset prices may be falling, increasing the risk of investment losses.
  • The Fund could lose money if a counterparty with which the Fund trades becomes unwilling or unable to meet its obligations, or as a result of failure or delay in operational processes or the failure of a third party provider.
  • Funds incur costs as a necessary part of buying and selling the underlying investments, these are otherwise known as portfolio transaction costs, and include charges such as broker commission and Stamp Duty.
  • Before investing in any of our funds you should satisfy yourself as to the suitability and the risks involved.
  • Summary of Investor rights
  • Janus Henderson Investors Europe S.A. may decide to terminate the marketing arrangements of this Collective Investment Scheme in accordance with the appropriate regulation.
  • Information on compliance with EU Sustainability related disclosures can be found here.
  • For detailed product information including the risks associated with investing please read the relevant Prospectus or Annual Report. Please refer to the prospectus of the UCITS and to the KID before making any final investment decisions.
  • The Legal Entity Identifier for this product is 5493002MVUQOZF2KCA11.

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